Patient Success Story: Treating Accutane-Induced Dry Eye With IPL, Meibomian Gland Probing & Steroid Lavage

Introduction: When Clear Skin Comes at a Cost

For individuals struggling with severe acne, Accutane (isotretinoin) often provides life-changing results. However, it can come with serious ocular side effects—most notably, chronic dry eye. In this patient success story, we explore how one individual overcame years of discomfort using advanced treatment options targeting Meibomian Gland Dysfunction (MGD).

The Hidden Impact of Accutane on Eye Health

After finishing a course of Accutane, our patient began to experience intense eye dryness, burning, and light sensitivity. Over-the-counter drops offered no relief. Standard treatments failed to address the root cause.

A comprehensive eye exam revealed significant Meibomian Gland Dysfunction (MGD)—a common but under-recognized consequence of isotretinoin therapy. Accutane works by reducing oil production, including in the meibomian glands, which are critical for maintaining a stable tear film. In this particular patient, the glands had become blocked due to scar tissue, leading to evaporative dry eye.

Diagnosis & Customized Treatment Plan

Upon Dr. Zimski's evaluation with advanced imaging and gland expression techniques, the patient's glands showed severe stagnation and fibrosis, consistent with Accutane-induced MGD.

The treatment plan involved a strategic combination of:

• IPL (Intense Pulsed Light) Therapy - Used to reduce periocular inflammation and stimulate Meibomian gland function, IPL helped reduce telangiectasias, inflammation and improve the lipid layer quality of the tear film.

• Meibomian Gland Probing - This step was critical. The glands were physically probed to break through fibrotic blockages, restoring ductal patency and allowing natural oil flow. For patients with periductal fibrosis, this is the only procedure that can restore meibomian gland function.

• Steroid Lavage - Following probing, a steroid solution was irrigated into the gland ducts to reduce inflammation and encourage healing. This also helped modulate the immune response that can provide lasting relief after mechanical blockages are cleared.

Results: Relief After Years of Frustration

After completing the multi-step treatment plan, the patient reported a dramatic reduction in symptoms. Their tear film stability improved, inflammation decreased, and meibomian gland function showed measurable recovery.

Perhaps most importantly, the emotional burden of constant discomfort was lifted. The patient described feeling “normal” again—able to work, read, and enjoy life without the constant distraction of dry, irritated eyes.

Key Takeaways

• Accutane-induced dry eye is often mismanaged when only artificial tears or superficial treatments are used.

• MGD is the core issue, and advanced diagnostics paired with targeted therapies are essential.

• Meibomian gland probing and steroid lavage are powerful tools when standard treatments fall short.

• IPL can complement these procedures by reducing inflammation and stimulating gland function.

Final Thoughts

Accutane doesn’t have to mean lifelong eye problems. With the right diagnosis and treatment plan, even the most stubborn cases of dry eye can find lasting relief. If you or someone you know is suffering from post-Accutane ocular issues, it’s crucial to seek out a dry eye specialist trained in advanced interventions like probing and IPL.

Dry eye may start on the surface, but for many patients, the path to healing runs deeper. To learn more, schedule an appointment today with Dr. Zimski.